Cullinan says zipalertinib plus chemotherapy meets PFS endpoint in Phase 3 REZILIENT3 lung cancer trial
Reuters2026/08/12 23:30Bitget offers one-stop trading for cryptocurrencies, stocks, and gold. Trade now!
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- Cullinan Therapeutics announced a planned interim analysis of the Phase 3 REZILIENT3 trial met its primary progression-free survival endpoint.
- Zipalertinib with platinum-based chemotherapy outperformed chemotherapy alone as first-line treatment for EGFR exon 20 insertion mutation non-small cell lung cancer.
- Safety in the zipalertinib arm was described as manageable, prompting the independent monitoring committee to recommend unblinding.
- Full results have not been presented yet; they are slated for release at a future international medical conference.
- Partners plan to pursue U.S. regulatory approval for the combination regimen in the first-line setting, pending FDA discussions.
Disclaimer:
This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Cullinan Therapeutics Inc. published the original content used to generate this news brief via Business Wire (Ref. ID: 20260812153742) on August 12, 2026, and is solely responsible for the information contained therein.
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